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Scientific Program

Program at a Glance

Daily Schedule Aug.23-27

Aug.22
(Sun)
8:30 - 16:00
    17:00 - 21:00
Opening Ceremony
Welcome Reception
FOCIS/JSI Immunology Update
Teaching Course for young
physicians, investigators
13:00 - 19:00
Registration
Aug.23
(Mon)
8:30
|
9:15
Master
Lecture

ML
9:30
|
12:00
Symposia
SY1-1
SY2-1
SY3-1
SY4-1
SY5-1
SY6-1
12:20
|
13:20
Lunchtime
Lectures

LL
13:30
|
15:00
Workshops
WS
15:10
|
16:40
Workshops
WS
17:00
|
18:00
Poster
Discussion

PP
18:15
|
20:00
Novartis
Award
Ceremony
Cocktail Party
 
Aug.24
(Tue)
8:30
|
9:15
Master
Lecture

ML
9:30
|
12:00
Symposia
SY1-2
SY2-2
SY3-2
SY4-2
SY5-2
SY6-2
12:20
|
13:20
Lunchtime
Lectures

LL
13:30
|
15:00
Workshops
WS
15:10
|
16:40
Workshops
WS
17:00
|
18:00
Poster
Discussion

PP
18:15
|
19:00
Master
Lectures

ML
 
  14:00 - 16:30
Special
Symposia for
Clinicians

CS-1
 
Aug.25
(Wed)
8:30
|
9:15
Master
Lecture

ML
9:30
|
12:00
Symposia
SY1-3
SY2-3
SY3-3
SY4-3
SY5-3
SY6-3
12:20
|
13:20
Lunchtime
Lectures

LL
13:30
|
15:00
Workshops
WS
15:10
|
16:40
Workshops
WS
17:00
|
18:00
Poster
Discussion

PP
18:15
|
19:00
Master
Lectures

ML
 
  14:00 - 16:30
Special
Symposia for
Clinicians

CS-2
  18:15
|
20:15
Virus Epidemic:
Influenza and
Foot-and-
Mouth Disease
IS-3
Aug.26
(Thu)
8:30
|
9:15
Master
Lecture
ML
9:30
|
12:00
Symposia
SY1-4
SY2-4
SY3-4
SY4-4
SY5-4
SY6-4
12:20
|
13:20
Lunchtime
Lectures
LL
13:30
|
15:00
Workshops
WS
15:10
|
16:40
Workshops
WS
17:00
|
18:00
Poster
Discussion
PP
18:15
|
19:00
Master
Lectures
ML
20:00
|
22:00
Official
Party

Meriken
Park Party
  14:00 - 16:30
Special
Symposia for
Clinicians
CS-3
 
Aug.27
(Fri)
8:30
|
9:15
Master
Lecture
ML
9:30
|
12:00
Symposia
SY1-5
SY2-5
SY3-5
SY4-5
SY5-5
SY6-5
12:20
|
13:20
Lunchtime
Lectures
LL
13:30
|
15:00
Workshops
WS
15:10
|
16:40
Workshops
WS
17:00
|

Closing
Ceremony
   

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Daily Program

Aug. 23  Aug. 24  Aug. 25  Aug. 26  Aug. 27  Daily Schedule Aug.23-27

This daily schedule shows the allotment of all the workshops.

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Keynote Lecture

A keynote lecture by a Nobel Prize Laureate in Physiology and Medicine will be given at the Opening Ceremony of the Congress.

August 22

Prof. David Baltimore (California Institute of Technology, USA)

"MicroRNA's and the Immune System”

Master Lectures

State of the art lectures delivered by prominent scientists and doctors who are active at the forefront of their fields.

August 23

Tadamitsu Kishimoto (Osaka University, Japan)

“IL-6 : Back to the Future”

Jules A. Hoffmann (Institut de Biologie Moléculaire et Cellulaire du CNRS, France)

“Innate immunity in Drosophila

August 24

Max D. Cooper (Emory University School of Medicine, USA)

“Evolution of Alternative Adaptive Immune Systems”

Klas Kärre (Karolinska Institute, Sweden)

“Education of natural killer (NK) cells by host MHC class I molecules”

William E. Paul (National Institute of Allergy and Infectious Diseases, USA)

“CD4 T cells: fates and functions”

Philippa Marrack (National Jewish Health, USA)

“The obsession of T cell receptors with MHC”

August 25

Fritz Melchers (Max Planck Institute for Infection Biology, Germany)

“Paradigms of B lymphocyte development, repertoire selection and central tolerance ”

Tak W. Mak (The Cambpell Family Institute for Breast Cancer Research,
University Health Network, Canada)

“Lymphocyte Homeostasis: To kill or be killed.”

Tasuku Honjo (Kyoto University, Japan)

“Topoisomerase 1 involvement in AID-induced S region cleavage and CSR”

August 26

Ralph M. Steinman (The Rockefeller University, USA)

“Vaccines that target dendritic cells”

Klaus Rajewsky (Children's Hospital Boston, USA)

“B-cell maintenance, response and surveillance”

Charles Dinarello (University of Coloraldo Denver, USA)

“IL-1beta and the spectrum of auto-inflammatory diseases”

Stefan H. E. Kaufmann (Max Planck Institute for Infection Biology, Germany)

“Learning from Life: Guidelines for Immunologic Control of the Most Successful Bacterial Pathogen on Our Globe ”

August 27

Emil R. Unanue (Washington University School of Medicine, USA)

“The unsolved mysteries of antigen presentation”

Irving Weissman (Stanford School of Medicine, USA)

“Normal & neoplastic stem cell”

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Symposia

30 Main Symposia on six tracks will feature 5-6 presentations per session, covering the latest updates and hot topics from basic to clinical studies.

Symposia Track 1: Infection and Immunity

Day 1 Monday, Aug.23

SY1-1: Innate Immunity I (Innate receptors)

Luke O'Neill (Trinity College, Ireland)

“Fine -tuning TLR and NLR signaling”

Shizuo Akira (Osaka University, Japan)

“Roles of TLR inducible genes revealed by gene targeting”

Jie-Oh Lee (Korea Advanced Institute of Science and Technology)

“Crystal structures of the TLR-ligand complexes”

Ruslan Medzhitov (Yale University School of Medicine, USA)

“Innate Control of Adaptive Immunity”

Jürg Tschopp (University of Lausanne, Switzerland)

“The inflammasomes”

Tadatsugu Taniguchi (University of Tokyo, Japan)

“Nucleic acid sensing and activation of immune responses”

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Day 2 Tuesday, Aug.24

SY1-2: Innate Immunity 2 (Innate cells)

Gordon Brown (University of Aberdeen, UK)

“Anti-fungal immunity”

Caetano Reis e Sousa (London Research Institute, UK)

“Innate regulation of adaptive immunity by dendritic cells”

Lewis Lanier (UCSF, USA)

“NK cells in viral immunity”

Adrian Hayday (King's College London, UK)

“Molecular mechanisms mediating the lymphoid stress-surveillance response”

Shigeo Koyasu (Keio University School of Medicine, Japan)

“Natural helper cell: a newly identified innate lymphocyte producing Th2 cytokines”

Marco Colonna (Washington University School of Medicine, USA)

“NK cells in mucosal Immunity”

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Day 3 Wednesday, Aug.25

SY1-3: Infection 1 Viral Infection

Takashi Fujita (Kyoto University, Japan)

“Regulation of the innate antiviral response by local condensation of IPS-1 mediated by mitochondrial dynamism”

Zhijian Chen (University of Texas at Dallas, USA)

“Biochemical dissection of antiviral signaling cascades”

Christine Biron (Brown University, USA)

“Communication between innate and adaptive immune responses to viral infections”

Wayne Yokoyama (Washington University School of Medicine, USA)

“Immune evasion of innate and adaptive immunity”

Stipan Jonjic (University of Rijeka, Croatia)

“Cytomegalovirus protein m04 abolishes NK cell activation via the “missing-self” recognition mechanism”

Akiko Iwasaki (Yale University School of Medicine, USA)

“Mucosal antiviral immunity”

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Day 4 Thursday, Aug.26

SY1-4: Infection 2 Bacterial Infection

Chihiro Sasakawa (University of Tokyo, Japan)

“Shigella circumvention of intestinal innate defense system”

Jenny Ting (University of North Carolina at Chapel Hill, USA)

“The NLR family in infection and immunity”

Alberto Mantovani (Istituto Clinico Humanitas and University of Milan, Italy)

“Humoral innte immunity as an integrated system:pentraxins as paradigm”

Yoichiro Iwakura (University of Tokyo, Japan)

“The roles of IL-17A/F in inflammation and host defense against infection”

Mitchell Kronenberg (La Jolla Institute for Allergy and Immunology, USA)

“Innate-like recognition of microbes by invariant natural killer T cells”

Arturo Zychlinsky (Max Planck Institute for Infection Biology, Germany)

“Neutrophil extracellular traps in infection and autoimmunity”

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Day 5 Friday, Aug.27

SY1-5: Infection 3 Protozoal and Helminth Infection

Adrian Hill (University of Oxford, UK)

“New vaccination approaches for malaria”

Paul Kaye (University of York, UK)

“Immune regulation in the Leishmania granuloma: Macrophages, T cells and more⋯.”

Alan Sher (National Institute of Allergy and Infectious Diseases, USA)

“Initiating and polarizing functions of dendritic cells in the immune response to parasites”

Kenji Nakanishi (Hyogo College of Medicine, Japan)

“Innate and acquired immunity in expulsion of intestinal nematode”

Thomas Wynn (National Institute of Health, USA)

“Role of Arginase-1 in suppressor macrophage activity revealed with cell-specific knockout mice”

Maria Yazdanbakhsh (Leiden University Medical Center, Netherlands)

“Modulation of the immune system by parasitic helminthes:how, why and so what?”

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Symposia Track 2: Tolerance/Autoimmunity

Day 1 Monday, Aug.23

SY2-1: Th17 / Treg

Shimon Sakaguchi (Kyoto University, Japan)

“Regulatory T cells for self-tolerance”

Ethan Shevach (National Institute of Allergy and Infectious Diseases, USA)

“Control of immune responses by natural and adaptive T regulatory cells”

Alexander Rudensky (Memorial Sloan Kettering and Howard Hughes Medical Institute, USA)

“Molecular determinants of differentiation and function of regulatory T cells”

Daniel Cua (Schering-Plough Biopharma, USA)

“Cytokine regulation of autoimmunity:targeting the Th17 immune pathway”

Vijay Kuchroo (Harvard Medical School, USA)

“Interplay between T-regs and Th17 cells”

Dan Littman (New York University School of Medicine, USA)

“Transcription factor networks in Th17 cell differentiation”

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Day 2 Tuesday, Aug.24

SY2-2: Autoimmune Mechanisms

Diane Mathis (Harvard Medical School, USA)

“The molecular mechanism of Aire”

Abul Abbas (University of California, San Francisco, USA)

“T-cell tolerance and autoimmunity”

Luciano Adorini (Intercept Pharmaceuticals, Italy)

“Control of autoimmune diseases by the vitamin D system and other nuclear receptor agonists”

Shigekazu Nagata (Kyoto University, Japan)

“Engulfment and degradation of dead cells”

Reinhold Schmidt (Medizinische Hochschule Hannover, Germany)

“Antibody-mediated inflammatory processes”

Betty Diamond (Feinstein Institute for Medical Research, USA)

“Neuropsychiatric disese and antibodies”

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Day 3 Wednesdy, Aug.25

SY2-3: Mucosal Immunity

Maria Rescigno (European Institute of Oncology, Italy)

“Dendritic cells in bacterial handling in the gut”

Yasmine Belkaid (National Institute of Allergy and Infectious Diseases, USA)

“Control of regulatory T cells by microbes”

Sidonia Fagarasan (RIKEN, Research Center for Allergy and Immunology, Japan)

“Adaptive immune regulation in the gut:T cell-dependent and T cell-independent IgA synthesis”

Fiona Powrie (University of Oxford, UK)

“The IL-23 pathway in intestinal inflammation”

David Artis (University of Pennsylvania, USA)

“Regulation of immunity and inflammation in the gut”

Richard Blumberg (Harvard Medical School, USA)

“Endoplasmic Reiculum Stress and Intestinal Inflammation”

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Day 4 Thursday, Aug.26

SY2-4: Tolerance & Transplantation

Ludger Klein (Ludwig-Maximilians-University, Germany)

“Autonomous role of medullary thymic epithelial cells in central CD4 T cell tolerance”

Mitsuru Matsumoto (University of Tokushima, Japan)

“Roles of thymic epithelial cells for the establishment of self-tolerance”

Christopher Goodnow (Australian National University, Australia)

“Multi-step breakdown of tolerance in autoimmunity”

David Wraith (University of Bristol, UK)

“Negative feedback mechanisms in peripheral tolerance”

Kathryn Wood (John Radcliffe Hospital, UK)

“Controlling rejection - a role of Treg and MSC”

Herman Waldmann (University of Oxford, UK)

“Mechanisms underlying infectioustolerance”

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Day 5 Friday, Aug.27

SY2-5: Immune Surveillance and Tumor Immunity

Robert Schreiber (Washington University School of Medicine, USA)

“Cancer Immunoediting: Basic mechanisms and therapeutic implications”

Takashi Nishimura (Hokkaido University, Japan)

“Overcoming immunosuppressive tumor-escape mechanisms by Th1 cell therapy
-From basic to clinical study-”

Eric Vivier (Marseille University, France)

“Regulation of natural killer cell function”

Michael Karin (University of California, San Diego, USA)

“Innate responses to injury and death as promoters of tumor progression and metastasis”

Dmitry Gabrilovich (H. Lee Moffitt Cancer Center, USA)

“Lipid accumulation and dendritic cell dysfunction in cancer”

Laurence Zitvogel (Institute Gustave Roussy, France)

“Molecular bases of the immunogenicity of cell death in cancer”

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Symposia Track 3: Development/Differentiation

Day 1 Monday, Aug.23

SY3-1: Early Lymphocyte Development

Ana Cumano (Pasteur Institute, France)

“Heterogeneity of the common lymphoid progenitors in fetal liver and bone marrow”

Hans-Reimer Rodewald (German Cancer Research Center, Germany)

“Fate mapping of early T-cell development”

Avinash Bhandoola (University of Pennsylvania, USA)

“Notch signals constrain the myeloid potential of early T cell progenitors”

Yousuke Takahama (University of Tokushima, Japan)

“Thymic microenvironments that shape T cell repertoire”

Ichiro Taniuchi (RIKEN, Research Center for Allergy and Immunology, Japan)

“Transcriptional control of helper versus cytotoxic lineage choice”

Paul Kincade (Oklahoma Medical Research Foudation, USA)

“Functional Diversity of Stem and Progenitor Cells”

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Day 2 Tuesday, Aug.24

SY3-2: Cellular Trafficking

Miriam Merad (Mount Sinai School of Medicine, USA)

“Functional Diversity of non lymphoid tissue DCs”

Ulrich von Andrian (Harvard Medical School, USA)

“Visualizing the immune response”

Ellen Robey (University of California Berkeley, USA)

“Visualizing Thymic Selection in situ”

Jason Cyster (UCSF, USA)

“Cell position control and humoral immunity”

Masayuki Miyasaka (Osaka University, Japan)

“How does a lipid mediator-generating enzyme, autotoxin, regulate lymphocyte trafficking across high endothelial venules?”

Takashi Nagasawa (Kyoto University, Japan)

“The chemokine CXCL12 and niches for hematopoietic stem cells and immune cells”

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Day 3 Wednesdy, Aug.25

SY3-3: Repertoire / Diversity (T and B)

Kristin Hogquist (University of Minnesota, USA)

“PLZF+ cells regulate the development of innate-like CD8 T cells through IL-4”

Marc Jenkins (University of Minnesota, USA)

“Determinants of naïve CD4+ T cell population size”

Michael McHeyzer-Williams (The Scripps Research Institute. USA)

“Follicular Helper T Cell Regulated B Cell Immunity”

David Nemazee (The Scripps Research Institute, USA  )

““Missing self” recognition by B cells”

Michel Nussenzweig (The Rockefeller University, USA)

“Antibody diversity and lymphoma”

Frederick Alt (Children's Hospital Boston, USA)

“Mechanisms of CSR and translocations”

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Day 4 Thursday, Aug.26

SY3-4: T and B Cell Memory

Rafi Ahmed (Emory University, USA)

“Human memory B cell response to pandemic H1N1 influenza virus infection”

Michael Bevan (University of Washington, USA)

“Cytotoxic T cell differentiation”

Stephen Schoenberger (La Jolla Institute for Allergy and Immunology, USA)

“Molecular regulation of T help for CTL”

Federica Sallusto (Institute for Research in Biomedicine, Switzerland)

“Human memory T cells”

Andreas Radbruch (Deutsches Rheuma-Forschungszentrum, Germany)

“Organisation of immunological memory by bone marrow stromal cells”

Mark Shlomchik (Yale University School of Medicine, USA)

“Signaling, Survival and Differentiation in the Germinal Center”

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Day 5 Friday, Aug.27

SY3-5: Inflammation / Cytokines

John O'Shea (NIAMS, NIH, USA)

“Transcriptional and epigenetic control of helper T cell differentiation”

Anne O'Garra (The MRC National Institute for Medical Research, UK)

“Regulation of IL-10 production by cells of the innate and adaptive immune response and implications for immune response to pathogens”

Frederic Geissmann (Centre for Molecular and Cellular Biology of Inflammation, UK)

“Differentiation and functions of 'mononuclear phagocytes' in vivo

Antonio Celada (Institute for Research in Biomedicine, Spain)

“Macrophages and inflammation:mechanisms of survival”

Xuetao Cao (Second Military Medical University, China)

“Cross regulation of TLR-triggered pro-inflammatory cytokine production”

Toshio Hirano (Osaka University, Japan)

“Role of interleukin 6 amplifier in autoimmune diseases and inflammation”

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Symposia Track 4: Lymphocyte Regulation

Day 1 Monday, Aug.23

SY4-1: Lymphocyte Signaling

Garry Nolan (Stanford University, USA)

“Single cell systems network analysis of autoimmune dysregulation”

Tomohiro Kurosaki (Osaka University and RIKEN Research Center for Allergy and Immunology, Japan)

“Store-operated Calcium Entry in B cells”

André Veillette (Clinical Research Institute of Motreal, Canada)

“SAP family adaptors in lymphocyte activation”

Arthur Weiss (University of California, San Francisco, USA)

“Regulation of tyrosine phosphorylation by the T cell antigen receptor”

Doreen Cantrell (University of Dundee, UK)

“Serine Kinases in T lymphocytes”

Pamela Schwartzberg (National Human Genome Institute, NIH, USA)

“Integrating T cell signals and effector cell function”

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Day 2 Tuesday, Aug.24

SY4-2: Antigen Presentation

Sebastian Amigorena (Institut Curie, France)

“Antigen cross presentation in dendritic cells”

Hidde Ploegh (Whitehead Institute for Biomedicl Research, USA)

“Transnuclear mice made by somatic cell nuclear transfer from B and T lymphocytes”

Christian Münz (University of Zürich, Switzerland)

“Viral regulation of macroautophagic antigen processing for MHC presentation”

Bernard Malissen (Centre d'Immunologie de Marseille-Luminy, France)

“Disentangling the complexity of the dendrtitic cell network present in the skin”

Christian Kurts (University of Bonn, Germany)

“Regulation of cross-priming by Chemokines”

William Heath (The University of Melbourne, Australia)

“Dendritic cell subsets involved in the initiation of CD8 T cell immunity to virus infection”

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Day 3 Wednesdy, Aug.25

SY4-3: Immuno Imaging

Michael Dustin (New York University School of Medicine, USA)

“Protein kinase C-θ mediates negative feedback on regulatory T cell function”

Ronald Germain (National Institute of Allergy and Infectious Diseases, NIH, USA)

In situ dynamics of T cell co-operation and effector activation analyzed by 2 photon microscopy”

Takashi Saito (RIKEN Research Center for Allergy and Immunology, Japan)

“Spatio-temporal regulation of T cell activation”

Mark Davis (Stanford University School of Medicine, USA)

“T cell recognition and repertoire selection”

Susan Pierce (National Institute of Allergy and Infectious Diseases, NIH, USA)

“The molecular basis of the initiation of B cell receptor signaling”

Facundo Batista (London Research Institute, UK)

“Early events in B cell activation and initiation of immune response”

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Day 4 Thursday, Aug.26

SY4-4: Transcriptional Control

Anjana Rao (Harvard Medical School, USA)

“Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells”

Richard Flavell (Yale University School of Medicine, USA)

“Regulation of immune response at the molecular level”

Cornelis Murre (University of California San Diego, USA)

“Regulatory Network that Orchestrates B cell development”

Ellen Rothenberg (California Institute of Technology, USA)

“Transcriptional regulation of T cell specification and commitment”

Stephen Nutt (The Walter and Eliza Hall Institute, Australia)

“The Transcriptional Regulation of Lymphocyte and Dendritic Cell Differentiation”

Kenneth Murphy (Washington University School of Medicine, USA)

“BATF family AP-1 transcription factors regulate immune lineage decisions”

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Day 5 Friday, Aug.27

SY4-5: Co-stimulation and Cell Communication

Hitoshi Kikutani (Osaka University, Japan)

“Semaphorins in immune cell communication”

Tania Watts (University of Toronto, Canada)

“TNFR family members in viral infection and CD8 T cell memory”

Arlene Sharpe (Harvard Medical School, USA)

“Roles of PD-1 and PD-L1 in regulating the balance between T cell activation and tolerance”

Christopher Rudd (University of Cambridge, UK)

“Coreceptor signalling and regulation of adaptive immunity”

Chen Dong (University of Texas, USA)

“Costimulation-dependent regulation of T cell tolerance and differentiation”

Carola Vinuesa (Australian National University, Australia)

“Sorting through the heterogeneity of T follicular helper cells”

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Symposia Track 5: Clinical Immunology 1 (JSCI)

Day 1 Monday, Aug.23

SY5-1: Cell Therapy

Jacque Banchereau (Baylor Institute for Immunology Research, USA)

“Harnessing Human Dendritic Cell Subsets for Improved Vaccines”

Antonio Uccelli (University of Genova, Italy)

“Mesenchymal stem cells: a new cell therapy for autoimmune diseases”

Philip Greenberg (University of Washington, USA)

“Overcoming obstacles to effective T cell therapy of malignant disease”

Samuel Strober (Stanford University School of Medicine, USA)

“Natural killer T cells, Treg cells, and their interactions after bone marrow transplantation”

Lorenzo Moretta (Instituto Giannina Gaslini, Italy)

“Natural killer cells in the therapy of high-risk leukemias”

Masaru Taniguchi (RIKEN Research Center for Allergy and Immunology, Japan)

“NKT cell-targeted adjuvant cell therapy-from basic to clinic”

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Day 2 Tuesday, Aug.24

SY5-2: Antibody Therapy

Jeffrey Ravetch (The Rockefeller University, USA)

“The antibody paradox: novel roles for Fc glycans”

James Allison (Memorial Sloan Kettering Cancer Center, USA)

“Immune checkpoint blockade in cancer therapy : new insights and opportunities”

Patrick Baeuerle (Micromet AG, Germany)

“T cell-engaging antibodies for cancer therapy”

Ronald Levy (Stanford University, USA)

“Antibody therapy of cancer, targeting the tumor and the host immune system”

Thomas Waldmann (National Cancer Institute,NIH, USA)

“Cytokine receptor directed monoclonal antibody mediated therapy of leukemia, Hodgkin's lymphoma and autoimmune diseases”

Marc Feldmann (Kennedy Institute of Rheumatology Division, UK)

“Anti TNF therapy : Why does it work and what comes next?”

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Day 3 Wednesdy, Aug.25

SY5-3: Vaccination (new adjuvants etc.)

Rino Rappuoli (Novartis Vaccines and Diagnostics, Italy)

“Vaccines to address the needs of a 21st century society”

Glen N. Barber (University of Miami School of Medicine, USA)

“Intracellular DNA signaling pathways and the regulation of innate and adaptive immunity”

Bali Pulendran (Emory Vaccine Center, USA)

“Modulating vaccine responses with innate immunity”

Bing Sun (Chinese Academy of Sciences, China)

“Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling”

Peter Ernst (University of Virginia, USA)

“Challenges in stimulating mucosal immunity to luminal pathogens: What we have learned from Helicobacter pylori”

Hiroshi Kiyono (The University of Tokyo, Japan)

“Mucosal Immunity for new generation of needl/syringe-and cold chain- free vaccine”

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Day 4 Thursday, Aug.26

SY5-4: Allergy

Stephen Galli (Stanford University School of Medicine, USA)

“Mast cells as positive and negative regulators of innate and acquired immunity”

Hajime Karasuyama (Tokyo Medical and Dental University Graduate School, Japan)

“Novel roles for basophils in allergy and immunity”

Yong-Jun Liu (The University of Texas, USA)

“TSLP leads the TH2 pathway to allergic inflammation”

Bart Lambrecht (University Ghent, Belgium)

“Epithelial and dendritic cell interactions at the origin of allergic asthma”

Rudolf Valenta (Medical University of Vienna, Austria)

“Vaccination against allergy”

Cezmi Akdis (Swiss Institute of Allergy and Asthma Research, Switzerland)

“Mechanisms of immune tolerance to allergens”

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Day 5 Friday, Aug.27

SY5-5: Mouse to Man

Markus Manz (University Hospital Zurich, Switzerland)

“Translation of pathogen signals into enhanced production of innate immune effector cells”

Riitta Lahesmaa (University of Turku, Finland)

“Molecular mechanisms of human T helper cell differentiation”

Hergen Spits (University of Amsterdam, The Netherlands)

“B cell responses in human immune system(HIS) mice”

Kazuhiko Yamamoto (The University of Tokyo, Japan)

“Immune responses in rheumatoid arthritis”

Markus Heim (University Hospital Basel, Switzerland)

“Interferon signaling in viral hepatitis”

Alain Fischer (Hospital Necker, France)

“Molecular defects of T cell immunity in humans”

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Symposia Track 6: Clinical Immunology 2 (FOCIS)

Day 1 Monday, Aug.23

SY6-1: Genetics of Autoimmunity

David Hafler (Yale School of Medicine, USA)

“The genetics of multiple sclerosis”

Takehiko Sasazuki (Kyusyu University, Japan)

“Immunogenetic risk factors for autoimmune thyroid disease and a novel transcriptional regulator ZFAT”

Judy Cho (Yale School of Medicine, USA)

“Genetics of autoimmunity”

Lars Klareskog (Karolinska Institute, Sweden)

“Genes, environment and immunity in rheumatoid arthritis”

Timothy Behrens (Genentech, USA)

“Genetics of SLE”

John D. Rioux (University of Montreal, Canada)

“How genetic studies of Crohn’s disease and ulcerative colitis have identified key immune pathways of health and disease”

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Day 2 Tuesday, Aug.24

SY6-2: Microbial triggers for inflammatory disease

Kiyoshi Takeda (Osaka University, Japan)

“Regulation of innate immune responses at the intestinal mucosa”

Takashi Yamamura (National Institute of Neuroscience, NCNP, Japan)

“Invariant T cells as sensors and regulators of commensal flora”

Marie Wahren-Herlenius (Karolinska Institute, Sweden)

“Ro52 in regulation of TLR signaling and induction of tissue inflammation”

Alexander Chervonsky (University of Chicago, USA)

“Commensal microbes and autoimmunity”

Howard Weiner (Harvard Medical School, USA)

“Induction of regulatory T cells by mucosal administration of aryl hydrocarbon receptor ligands and anti-CD3 monoclonal antibody in animals and humans”

Hilde Cheroutre (La Jolla Institute for Allergy and Immunology, USA)

“Operating with a fake ID at the border: Lineage switch of mucosal CD4T cells”

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Day 3 Wednesdy, Aug.25

SY6-3: Treg Therapy and Plasticity

Jochen Huehn (Helmholtz-Centre for Infection Research, Germany)

“Epigenetic control of Foxp3 expression: the key to a stable Treg lineage?”

Shohei Hori (RIKEN Research Center for Allergy and Immunology, Japan)

“Stability and plasticity in regulatory Tcell differentiation”

Steven Ziegler ( Benaroya Research Institute, USA)

“Factors that Regulate iTreg Generation”

Lucienne Chatenoud (Hôpital Necker-Enfants Malades, France)

“The challenge of immune tolerance induction in primed hosts”

Matthias Edinger (Klinikum der Universität Regensburg, Germany)

“Adoptive Treg cell transfer in allogeneic stem cell transplantation”

Maria-Grazia Roncarolo (San Raffaele Scientific Institute, Italy)

“Induction and function of antigen-specific type 1 regulatory T (Tr1) cells.”

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Day 4 Thursday, Aug.26

SY6-4: Pathophysiology and Therapy of Autoimmune Disease

Ann Marshak-Rothstein (University of Massachusetts, USA)

“Activation and Inhibition of Autoreactive B cells”

Bana Jabri (University of Chicago, USA)

“Interplay between adaptive and innate immunity in celiac disease”

Hartmut Wekerle (Max Planck Institute of Neurobiology, Germany)

“Completing a Jigsaw Puzzle: Experimental Studies of the Immune Pathogenesis of Multiple Sclerosis”

Sander van Deventer (Leiden University Medical Center, The Netherlands)

“Treatment of immune -mediated inflammatory disease: past and future”

Pierre Miossec (University of Lyon, France)

“IL-17 family members: contribution to joint inflammation and destruction”

Josef Smolen (Medical University of Vienna, Austria)

“Novel pathogenetic and therapeutic insights in rheumatoid arthritis”

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Day 5 Friday, Aug.27

SY6-5: Genes and pathways in inflammatory diseases

Gabriel Nunez (University of Michigan)

“Function of NLRs in innate immunity and disease”

Eric Meffre (Yale University School of Medicine, USA)

“Human B-cell tolerance checkpoints in health and autoimmunity”

Frank Nestle (Guy's Hospital, UK)

“Skin inflammation: from genes to function and targeted therapy”

Virginia Pascual (Baylor Institute for Immunology Research, USA)

“Neutrophils are major inducers of type I Interferon production in human lupus”

Kouji Matsushima (University of Tokyo, Japan)

“Chemokines as therapeutic targets of inflammatory diseases and cancer”

Edward Wakeland (UT Southwestern Medical Center at Dalls, USA)

“Genomic analysis of susceptibility to SLE in humans”

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Workshops

More than 100 workshops are planned during the Congress period. Selected papers from submitted abstracts will be presented.

For workshop allotment, please look at the daily schedule.

Daily Schedule Aug.23-27

Workshop and Poster Schedule   WorkshopInstruction for Presentation

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Poster Sessions

All accepted abstracts will be presented as poster presentations. Poster Sessions are scheduled at 17:00 – 18:00 hours every day, except Friday, August 27th.

Please click on the button below for poster schedule(PDF).
Individual poster schedule and board number can be found using the PDF search function.

Poster Schedule and Board No.   Poster Map

For instruction for presentation, please click here.

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Lunchtime Lectures

Lunchtime Lectures are scheduled every day at 12:20 – 13:20 hours.
Currently the following speakers are scheduled.

Monday, August 23

Foo Y. Liew (University of Glasgow, UK)

“Novel cytokines in infection and inflammation”

Ifor Williams (Emory University School of Medicine, USA)

“Homeostatic interactions between the intestinal microbiome and the mucosal immune system”

Masaru Ishii (Osaka University, Japan)

“Dynamic live imaging of bone marrow cells by using intravital 2-photon microscopy”

Keishi Fujio (The University of Tokyo Hospital, Japan)

“Immunological intervention strategies aimed at regulatory T cells”

Masayuki Amagai (Keio University School of Medicine, Japan)

“Pemphigus vulgaris as a paradigm of autoimmune disease”

P Sriramarao (University of Minnesota, USA)

“Eosinophils, trafficking and allergic inflammation”

Sergio Romagnani (University of Florence, Italy)

“Human Th17 cells”



Tuesday, August 24

Warren Leonard (National Heart, Lung and Blood Institute, USA)

“Cytokines that share the common cytokine receptor gamma chain: old ideas and new lessons”

Tsutomu Takeuchi (Keio University School of Medicine, Japan)

“From the Results of the REtrospective ACTemra Investigation for Optimal Needs of RA patients (REACTION Study) in Daily Practice in Japan.”

Antonio Lanzavecchia (Institute for Research in Biomedicine, Switzerland)

“Dissecting the human T and B cell response to pathogens”

Ihor Lemischka (The Mount Sinai Medical Center, USA)

“Pursuing Pluripotency”

Hiromitsu Nakauchi (The University of Tokyo, Japan)

“Cytometry technologies for analysis of very small numbers of cells”

Ivan Lefkovits (University Hospital Basel, Switzerland)

“From clonal selection to Basel Institute and beyond”

Imran H. Khan (University of California, Davis, USA)

“New Paradigm in Tuberculosis Serodetection: Computational Analysis to Classify Profiles of anti-M. tb. Antibodies by Multiplex Microbead Arrays”



Wednesday, August 25

Hiroshi Takayanagi (Tokyo Medical and Dental University, Japan)

“RANKL and Osteoimmunology”

Richard Steven Blumberg (Harvard Medical School, USA)

“Regulation of lymphocyte function by carcinoembryonic antigen adhesion molecule 1: implications for inflammation and cancer ”

Andy Kokaji (STEMCELL Technologies Inc., Canada)

“Column-free methods for the fast and versatile isolation of highly purified, functional and expandable human regulatory T cell populations”

Yoshiya Tanaka (University of Occupational & Environmental Health, Japan)

“Paradigm shift of the treatment of rheumatoid arthritis by TNF-targeting biologics”

Kenji Kabashima (Kyoto University Graduate School of Medicine, Japan)

“Recent advances in the pathomechanism of psoriasis”

Ken-ichiro Seino (Hokkaido University, Japan)

“Approach to new immune cell therapies in the age of regenerative medicine”

Andreas Strasser (The Walter and Eliza Hall Institute of Medical Research, Australia)

“The many roles of apoptotic cell death in the immune system”

Cornelis Melief (Leiden University Medical Centre, Netherlands)

“Succesful Immunotherapy of established lesions induced by high risk HPV”



Thursday, August 26

Josef Smolen (Medical University of Vienna, Austria)

“Current status of therapy of inflammatory diseases with non-biological and biological agents”

Alan Aderem (Institute for Systems Biology, USA)

“A system's approach to dissecting immunity”

Jack Keene (Duke University Medical Center, USA)

“Emerging Tools for Exploring RNA Regulation”

Shimon Sakaguchi (Kyoto University, Japan)

“Regulatory T cells for immunological tolerance and immune homeostasis”



Friday, August 27

Noboru Mizushima (Tokyo Medical and Dental University, Japan)

“Physiological roles of autophagy in mammals”

Sakae Tanaka (The University of Tokyo, Japan)

“Regulation of apoptosis and function of osteoclasts by Bcl-2 family proteins”

Hiroshi Shimizu (Hokkaido University Graduate School of Medicine, Japan)

“Humanization of autoantigen to develop novel mouse models of autoimmunity”

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Special Symposia for Clinicians

Tuesday, August 24  14:00-16:30

CS1 “Progress of cancer immunotherapy”

Chairpersons: Nicholas Restifo (Maryland, USA) and Yutaka Kawakami (Tokyo, Japan)

Yutaka Kawakami (Keio University, Japan)

“Immunosuppression by human cancer cells and it's control for effective immunotherapy”

Ryuzo Ueda & Takashi Ishida (Nagoya City University, Japan)

“Therapeutic anti-CCR4 antibody: current status and future directions”

Noriyuki Sato (Sapporo Medical University, Japan)

“Immunotherapeutic clinical trial of survivin-based tumor antigens and manipulation of antigenicity enhancement by HSP90.”

Lieping Chen (Johns Hopkins University, USA)

“B7-H1/PD-1 immunomodulatory pathway, a journey for cure”

Nicholas Restifo (Surgery BR NCI, USA)

“Adoptive transfer of stem-like T cells: The future of cancer immunotherapy”

Hiroshi Shiku (Mie University, Japan)

“Gene modified T cell therapy targeting cancer-testis antigen”




Wednesday, August 25  14:00-16:30

CS2
“Present state and future of biologics in autoimmune diseases I: Cytokines”

Chairpersons: Josef Smolen (Vienna, Austria) and Yoshiya Tanaka (Kitakyushu, Japan)

Marc Feldmann (Kennedy Institute of Rheumatology, UK)

“Anti-cytokine biologicals: Prospects for the future”

Josef Smolen (Medical University of Vienna, Austria)

“IL-6 in arthritis”

Frank Nestle (King’s College London and Guy’s & St. Thomas Hospitals, UK)

“Cytokines in skin autoimmune diseases”

Toshifumi Hibi (Keio University Hospital, Japan)

“Cytokines in IBD”

Wim B van den Berg (Radboud University Nijmegen Medical Centre, Netherlands)

“IL-17 in autoimmunity”




Thursday, August 26  14:00-16:30

CS3
“Present state and future of biologics in autoimmune diseases II: Immune cells”

Chairpersons: Iain McInnes (Glasgow, UK) and Kazuhiko Yamamoto (Tokyo, Japan)

Iain McInnes (University of Glasgow, Glasgow Biomedical Research Center, UK)

“Placing T cell targeting in the context of immune modulatory therapeutics in a new decade?”

Joseph A. Markenson (Weil Cornell Medical College, USA)

“Efficacy and safety of T-Cell modulation in rheumatoid arthritis”

Joan T. Merrill (University of Oklahoma Health Science Center, USA)

“T Cell Targeted Therapies in Systemic Lupus Erythematosus”

Moncef Zouali (Inserm, France)

“B lymphocyte-based therapies in autoimmune diseases”

Yoshiya Tanaka (University of Occupational and Environmental Health, Japan)

“B cell depletion in SLE”


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Virus Epidemic: Influenza and Foot-and-Mouth Disease

Wednesday, August 25, 18:15 – 20:15

Yoshihiro Kawaoka (University of Tokyo, Japan)

“2009 Pandemic Influenza”

Peter Doherty (University of Melbourne, Australia)

“Immunity to Influenza”

Takeshi Kasai (CSR World Health Organization, Phillipines)

“Pandemic influenza A (H1N1) 2009 and its response”

Bryan Charleston (Institute of Animal Health,UK)

“Hunting foot-and-mouth disease virus”

William T. Golde (Plum Island Animal Disease Center, USA)

“Development of New Approaches in Vaccine Design and Delivery for Rapid Protection Against Foot-and-Mouth Disease”

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FOCIS/JSI Immunology Update Special Teaching Course

FOCIS/JSI Immunology Update Special Teaching Course has been fully booked. Thank you.

This teaching course will be a special opportunity for young physicians and investigators to gain an overview of the forefront of immunology research.

Date Sunday August 22, 2010, 8:30 – 16:00
Venue 3rd floor International Conference Room, Kobe International Conference Center
Maximum participants 150, accepted in order of application
Course fee Free of charge
Conditions Applicants must be registered ICI2010 participants and have paid the congress registration fee
Language English
Instructors Abul K. Abbas, MD: UCSF, San Francisco, USA
Andrew H. Lichtman, MD, PhD: Harvard Medical School, Boston, USA

Program

Course agenda for FOCIS/JSI Immunology Update Special Teaching Course has been revised. Please see below new agenda and updated course material.

08:30 Introduction to the Immune System (Abbas)
09:00 Antigen Presentation, Innate Immunity (Lichtman)
10:00 T Cell Activation and Costimulation (Abbas)
11:00 Break
11:15 T Cell Subsets, Cytokines (Lichtman)
12:15 Lunch Break
13:00 B Cells and Antibodies (Lichtman)
14:00 Tolerance and Immune Regulation (Abbas)
15:00 Break
15:15 Autoimmunity and Immunological Diseases (Abbas)
16:00 Adjourn

Course Material

These PDF files are the course materials to be used at FOCIS/JSI Immunology Update Special Teaching Course on August 22. The course participants will receive the same at the class.

At the end of the course, the participants will receive a certificate of attendance signed by the course instructors, Drs. Abul K. Abbas and Andrew H. Lichtman.

1. Introduction      2. Innate imm, Ag pres

3. T cell activation      4. Effector T cells, Cytokines

5. B cells      6. Tolerance and regulation

7. Autoimmune diseases      

*FOCIS/JSI Immunology Update Special Teaching Course is fully booked. Thank you.

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