Luke O'Neill (Trinity College, Ireland)
“Fine -tunig TLR and NLR signaling”
Shizuo Akira (Osaka University, Japan)
“Toll-like receptors and immune responses”
Kate Fitzgerald (University of Massachusetts Medical School, USA)
“DNA sensing in innate immunity”
Ruslan Medzhitov (Yale University School of Medicine, USA)
“Host defense mechanism”
Jürg Tschopp (University of Lausanne, Switzerland)
“The inflammasomes”
Tadatsugu Taniguchi (University of Tokyo, Japan)
“Nucleic acid sensing and activation of immune responses”
Gordon Brown (University of Aberdeen, UK)
“Anti-fungal immunity”
Caetano Reis e Sousa (London Research Institute, UK)
“Innate regulation of adaptive immunity by dendritic cells”
Lewis Lanier (UCSF, USA)
“NK cells in viral immunity”
Adrian Hayday (King's College London, UK)
“Molecular mechanisms mediating the lymphoid stress-surveillance response”
Albert Bendelac (University of Chicago, USA)
“Development of innate-like lymphocytes”
Marco Colonna (Washington Univ. School of Medicine, USA)
To be announced
Takashi Fujita (Kyoto University, Japan)
“Cytoplasmic viral RNA sensors”
Christine Biron (Brown University, USA)
“Communication innate and adaptive immune responses to viral infections”
Akiko Iwasaki (Yale University School of Medicine, USA)
“Mucosal antiviral immunity”
Zhijian Chen (University of Texas at Dallas, USA)
“Biochemical dissection of antiviral signaling cascades”
Wayne Yokoyama (Washington University School of Medicine, USA)
“Immune evasion of innate and adaptive immunity”
Stipan Jonjic (University of Rijeka, Croatia)
“Regulation of NK cell response by cytomegalovirus”
Arturo Zychlinsky (Max Planck Institute for Infection Biology, Germany)
“Neutrophil extracellular traps in infection and autoimmunity”
Alberto Mantovani (Istituto Clinico Humanitas, Italy)
“Humoral innte immunity as an integrated system:pentraxins as paradigm”
Yoichiro Iwakura (University of Tokyo, Japan)
“The role of IL-17A/F for the defense against infection”
Jenny Ting (University of North Carolina at Chapel Hill, USA)
“The NLR family in infection and immunity”
Mitchell Kronenberg (La Jolla Institute for Allergy and Immunology, USA)
“Innate-like recognition of microbes by invariant natural killer T cells”
Chihiro Sasakawa (University of Tokyo, Japan)
“Shigella circumvention of intestinal innate defense system”
Adrian Hill (University of Oxford, UK)
“New vaccination approaches for malaria”
Paul Kaye (University of York, UK)
“Mononuclear phagocyte function in experimental leishmaniases”
Alan Sher (National Institute of Allergy and Infectious Diseases, USA)
“Pathways of innate resistance in mycobacterial infection”
Thomas Wynn (National Institute of Health, USA)
“Role of Arginase-1 in the function of suppressor macrophages”
Kenji Nakanishi (Hyogo College of Medicine, Japan)
“Innate and acquired immunity in expulsion of intestinal nematode”
Maria Yazdanbakhsh (Leiden University Medical Center, Netherlands)
“Modulation of the immune system by parasitic helminthes:how and why”
Shimon Sakaguchi (Kyoto University, Japan)
“Regulatory T cells for self-tolerance”
Alexander Rudensky (Memorial Sloan Kettering & Howard Hughes Medical Institute, USA)
“Molecular determinants of differentiation and function of regulatory T cells”
Dan Littman (New York University School of Medicine, USA)
“Transcription factor networks in Th17 cell differentiation”
Ethan Shevach (National Institute of Allergy and Infectious Diseases, USA)
“Control of immune responses by natural and adaptive T regulatory cells”
Vijay Kuchroo (Harvard Medical School, USA)
“Interplay between T-regs and Th17 cells”
Daniel Cua (Schering-Plough Biopharma, USA)
“Cytokine regulation of autoimmunity: targeting the Th17 immune pathway”
Betty Diamond (Feinstein Institute for Medical Research, USA)
“Neuropsychiatric disease and antibodies”
Diane Mathis (Harvard Medical School, USA)
“Molecules and cells controllling autoimmunity”
Luciano Adorini (Intercept Pharmaceuticals, Italy)
“Nuclear receptors in the pathogenesis and treatment of autoimmune diseases”
Shigekazu Nagata (Kyoto University, USA)
“Engulfment and degradation of dead cells”
Reinhold Schimidt (Medizinische Hochschule Hannover, Germany)
“Antibody-mediated inflammatory processes”
Abul Abbas (UCSF, USA)
“T-cell tolerance and autoimmunity”
Maria Rescigno (European Institute of Oncology, Italy)
“Dendritic cells in bacterial handling in the gut”
Fiona Powrie (University of Oxford, UK)
To be announced
Yasmine Belkaid (National Institute of Health, USA)
“Control of regulatory T cells by microbes”
Sidonia Fagarasan (RIKEN, Research Center for Allergy and Immunology, Japan)
“Adaptive immune regulation in the gut: T cell-dependent and T cell-independent IgA synthesis”
David Artis (University of Pennsylvania, USA)
“Regulation of immunity and inflammation in the gut”
Richard Blumberg (Harvard Medical School, USA)
“Endoplasmic reiculum stress and intestinal inflammation”
Ludger Klein (Ludwig-Maximilians-University, Germany)
“The autonomous role of medullary thymic epithelial cells for CD4 T cell tolerance”
Mitsuru Matsumoto (University of Tokushima, Japan)
“Roles of thymic epithelial cells for the establishment of self-tolerance”
Christopher Goodnow (Australian National University, Australia)
“Multi-step breakdown of tolerance in autoimmunity”
David Wraith (University of Bristol, UK)
“Negative feedback mechanisms in peripheral tolerance”
Kathryn Wood (John Radcliffe Hospital, UK)
“Controlling rejection - a role of Treg and MSC”
Herman Waldmann (University of Oxford, UK)
“Mechanisms underlying infectioustolerance”
Michael Karin (University of California, San Diego, USA)
“Innate responses to injury and death as promoters of tumor progression and metastasis”
Laurence Zitvogel (Institute Gustave Roussy, France)
“Molecular bases of the immunogenicity of cell death in cancer”
Robert Schreiber (Washington University School of Medicine, USA)
“Cancer immunoediting: mechanisms and therapeutic applications”
Dmitry Gabrilovich (H. Lee Moffitt Cancer Center, USA)
“Myeloid-derived suppressor cells and immune response incancer”
David Raulet (University of California Berkeley, USA)
“Regulation of NK cell responses to tumors and normal tissues”
Eric Vivier (Marseille University, France)
“Regulation of Natural killer cell function”
Paul Kincade (Oklahoma Medical Research Foudation, USA)
“Dynamic replenishment of the immune system”
Harald von Boehmer (Dana-Farber Cancer Institute, USA)
“Early lineage decision in T lymphocyte development”
Ichiro Taniuchi (RIKEN, Research Center for Allergy and Immunology, Japan)
“Transcriptional control of helper versus cytotoxic lineage choice”
Ana Cumano (Pasteur Institute, France)
“Lymphopoiesis during embryonic development”
Yousuke Takahama (University of Tokushima, Japan)
“Thymic microenvironments that shape T-cell repertoire”
Hans-Reimer Rodewald (University Hospital Ulm, Germany)
“Fate mapping of early T-cell development”
Ulrich von Andrian (Harvard Medical School, USA)
“Visualizing the immune response”
Takashi Nagasawa (Kyoto University, Japan)
“The chemokine CXCL12 and niches for hematopoietic stem cells and immune cells”
Ellen Robey (University of California Berkeley, USA)
“In situ imaging of T cells in action”
Miriam Merad (Mount Sinai School of Medicine, USA)
“Functional diversity of non lymphoid tissue DCs”
Jason Cyster (UCSF, USA)
“Cell position control and humoral immunity”
Masayuki Miyasaka (Osaka University, Japan)
“Lysophospholipid signaling regulates lymphocyte trafficking across high endothelial venules”
Frederick Alt (Children's Hospital Boston, USA)
“Mechanisms of CSR and translocations”
Michel Nussenzweig (The Rockefeller University, USA)
“Antibody diversity and lymphoma”
Michael McHeyzer-Williams (The Scripps Research Institute. USA)
To be announced
Marc Jenkins (University of Minnesota, USA)
“Determinants of naïve CD4+ T cell population size”
Mark Schlissel (University of California Berkeley, USA)
“Transcriptional regulation o fV(D)J recombination”
Kristin Hogquist (University of Minnesota, USA)
“Thymic selection”
Rafi Ahmed (Emory University, USA)
“Memory T cell differentiation”
Michael Bevan (University of Washington, USA)
“Cytotoxic T cell differentiation”
Stephen Schoenberger (La Jolla Institute for Allergy and Immunology, USA)
“Molecular regulation of T help for CTL”
Mark Shlomchik (Yale University School of Medicine, USA)
“Development, selection and function of memory B cells”
Andreas Radbruch (Deutsches Rheuma-Forschungszentrum, Germany)
To be announced
Federica Sallusto (Institute for Research in Biomedicine, Switzerland)
“Human memory T cells”
Antonio Celada (Institute for Research in Biomedicine, Spain)
“Macrophages and inflammation:mechanisms of survival”
Prof. Xuetao Cao (Second Military Medical University, China)
“New subsets of immune cells for negative regulation of immune response and inflammation”
Frederic Geissmann (Centre for Molecular and Cellular Biology of Inflammation, UK)
“Cytokine production by monocytes”
John O'Shea (NIAMS, NIH, USA)
“Transcriptional and epigenetic control of helper T cell differentiation”
Toshio Hirano (Osaka University, Japan)
“Role of interleukin 6 amplifier in autoimmune diseases and inflammation”
Anne O'Garra (The MRC National Institute for Medical Research, UK)
“Regulation of cytokines in the immune response”
Arthur Weiss (UCSF, USA)
“Regulation of tyrosine phosphorylation by the T cell antigen receptor”
André Veillette (Clinical Research Institute of Motreal, Canada)
“SAP family adaptors in lymphocyte activation”
Tomohiro Kurosaki (RIKEN Research Center for Allergy and Immunology, Japan)
“Activation mechnism of memory B cells”
Doreen Cantrell (University of Dundee, UK)
“Metabolism, migration and memory”
Garry Nolan (Stanford University, Japan )
“Single cell systems network analysis of autoimmune dysregulation”
Pamela Schwartzberg (National Human Genome Institute, NIH, USA)
“Integrating T cell signals and effector cell function”
Hidde Ploegh (Whitehead Institute for Biomedicl Research, USA)
“Molecular aspects of antigen presentation and activation of antigen presenting cells”
William Heath (The University of Melbourne, Australia)
“Dendritic cell subsets involved in the initiation of CD8 T cell immunity to virus infection”
Peter Cresswell (Yale University School of Medicine, USA)
“Functions of the peptide loading complex”
Sebastian Amigorena (Institut Curie, France)
“Antigen cross presentation in dendritic cells”
Bernard Malissen (Centre d'Immunologie de Marseille-Luminy, France)
“Disentangling the complexity of the dendrtitic cell network present in the skin”
Christian Münz (University of Zürich, Switzerland)
“Viral regulation of macroautophagic antigen processing for MHC presentation”
Michael Dustin (New York University School of Medicine, USA)
“Role of mechanics in T cell receptor signaling”
Ronald Germain (National Institute of Allergy and Infectious Diseases, NIH, USA)
“In situ dynamics of T cell co-operation and effector activation analyzed by 2 photon microscopy”
Mark Davis (Stanford University School of Medicine, USA)
“T cell recognition and repertoire selection”
Takashi Saito (RIKEN Research Center for Allergy and Immunology, Japan)
“Spatio-temporal regulation of T cell activation”
Susan Pierce (National Institute of Allergy and Infectious Diseases, NIH, USA)
“A conformation-induced oligomerization model for B cell receptor microclustering and signaling”
Facundo Batista (London Research Institute, UK)
“Early events in B cell activation and initiation of immune response”
Anjana Rao (Harvard Medical School, USA)
“Calcium signaling and gene expression in lymphocytes”
Richard Flavell (Yale University School of Medicine, USA)
“Regulation of immune response at the molecular level”
Cornelis Murre (University of California San Diego, USA)
“The 3D-structure of the immunoglobulin heavy chain locus”
Ellen Rothenberg (California Institute of Technology, USA)
“Transcriptional regulation of T cell specification and commitment”
Meinrad Busslinger (Research Institute of Molecular Pathology, USA)
“Transcriptional control of early lymphocyte development”
Kenneth Murphy (Washington University School of Medicine, USA)
“Transcriptional control of macrophages and dendritic cells”
Hitoshi Kikutani (Osaka University, Japan)
“Semaphorins in immune cell communication”
Carl Ware (La Jolla Institute for Allergy and Immunology, USA)
“The LIGHT-HVEM-BTLA consignaling in immune activation and viral evasion”
Carola Vinuesa (Australian National University, Australia)
“Regulation of Tfh help to B cells”
Christopher Rudd (University of Cambridge, UK)
“Coreceptor signalling and regulation of adaptive immunity”
Arlene Sharpe (Harvard Medical School, USA)
“Roles of PD-1 and PD-L1 in regulating the balance between T cell activation and tolerance”
Chen Dong (University of Texas, USA)
“Costimulation-dependent regulation of T cell tolerance and differentiation”
Jacque Banchereau (Baylor Institute for Immunology Research, USA)
“Dendritic cell based vaccines”
Antonio Uccelli (University of Genova, Italy)
“Mesenchymal stem cells: a new cell therapy for autoimmune diseases”
Philip Greenberg (University of Washington, USA)
“Overcoming obstacles to effective T cell therapy of malignant disease”
Masaru Taniguchi (RIKEN Research Center for Allergy and Immunology, Japan)
“NKT cell-targeted adjuvant cell therapy-from basic to clinic”
Lorenzo Moretta (Instituto Giannina Gaslini, Italy)
“Narural killer cells in the therapy of high-risk leukemias”
Samuel Strober (Stanford, USA)
“Regulatory T cell interactions after hematopoietic cell transplantation for leukemia and lymphoma”
Marc Feldmann (Kennedy Institute of Rheumatology Division, UK)
To be announced
Jeffrey Ravetch (The Rockefeller University, USA)
“Diversity of antibody effector functions”
James Allison (Memorial Sloan Kettering Cancer Center, USA)
“Immune checkpoint blockade in cancer therapy : new insights and opportunities”
Ronald Levy (Stanford University, USA)
“Antibody therapy of cancer, targeting the tumor and the host immune system”
Thomas Waldmann (National Cancer Institute,NIH, USA)
“Cytokine receptor directed monoclonal antibody mediated therapy of leukemia, Hodgkin's lymphoma and autoimmune diseases”
Patrick Baeuerle (Micromet AG, Germany)
“T cell engaging antibodies for cancer therapy”
Yvette van Kooyk (VUMC, The Netherlands)
“Glyco-vaccines for DC targeting”
Bali Pulendran (Emory Vaccine Center, USA)
“Modulating vaccine responses with innate immunity”
Larry Steinman (Palo Alto, USA)
“Trials of antigen specific DNA vaccines for T1DM and multiple sclerosis in man”
Hiroshi Kiyono (The University of Tokyo, Japan)
“Muco Rice : new generation of needl/syringe-and cold chain- free vaccine”
Glen N. Barber (University of Miami School of Medicine, USA)
“Intracellular DNA signaling pathways and the regulation of innate and adaptive immunity”
Rino Rappuoli (Novartis Vaccines and Diagnostics, Italy)
To be announced
Stephen Galli (Stanford University School of Medicine, USA)
“Mast cells as positive and negative regulators of innate and acquired immunity”
Hajime Karasuyama (Tokyo Medical and Dental University Graduate School, Japan)
“Novel roles for basophils in allergy”
Rudolf Valenta (Medical University of Vienna, Austria)
“Vaccination against allergy”
Yong-Jun Liu (The University of Texas, USA)
“TSLP leads the TH2 pathway to allergic inflammation”
Cezmi Akdis (Swiss Institute of Allergy and Asthma Research, Switzerland)
“Mechanisms of immune tolerance to allergens”
Bart Lambrecht (University Ghent, Belgium)
“Studying epithelial DC interactions in Th2 immunity”
Alain Fischer (Hospital Necker, France)
“Molecular defects of T cell immunity in humans”
Riitta Lahesmaa (Turku, Finland)
To be announced
Kazuhiko Yamamoto (The University of Tokyo, Japan)
“Immune responses in rheumatoid arthritis”
Hergen Spits (University of Amsterdam, The Netherlands)
“B cell responses in human immune system (HIS) mice”
Markus Heim (University Hospital Basel, Switzerland)
“Interferon signaling in viral hepatitis”
Markus Manz (University Hospital Zurich, Switzerland)
“Stromal cells translate pathogen signals into production of innate immune effector cells ”
David Hafler (Yale School of Medicine, USA)
“The genetics of multiple sclerosis”
Judy Cho (Yale School of Medicine, USA)
“Genetics of autoimmunity”
Lars Klareskog (Karolinska Institute, Sweden)
“Genes, environment and immunity in rheumatoid arthritis”
Tim Behrens (Genentech, USA)
“Genetics of SLE”
John Rioux (Montreal, Canada)
To be announced
Takehiko Sasazuki (Kyusyu University, Japan)
“Genetics of autoimmune thyroid diseases - from HLA through whole genome”
Howard Weiner (Harvard Medical School, USA)
“Characteristics and function of mucosally induced Tregs”
Marie Wahren-Herlenius (Karolinska Institute, Sweden)
“Ro52 in regulation of TLR signaling and induction of tissue inflammation”
Alexander Chervonsky (University of Chicago, USA)
“Commensal microbes and autoimmunity”
Hilde Cheroutre (La Jolla Institute for Allergy and Immunology, USA)
“Operating with a fake ID at the border: Lineage switch of mucosal CD4T cells”
Kiyoshi Takeda (Osaka University, Japan)
“Regulation of innate immune responses at the intestinal mucosa”
Takashi Yamamura (National Institute of Neuroscience, NCNP, Japan)
“Invariant T cells as sensors and regulators of commensal flora”
Matthias Edinger (Klinikum der Universität Regensburg, Germany)
“Adaptive Treg cell transfer in allogeneic stem cell transplantation”
Maria Grazia Roncarolo (San Raffaele Scientific Institute, Italy)
“IL-10 secreting type 1 regulatory T cells in rodents and humans”
Jeffrey Bluestone (UCSF, USA)
“Treg stability and therapeutic application in autoimmunity”
Casey Weaver (University of Alabama, USA)
To be announced
Shohei Hori (RIKEN Research Center for Allergy and Immunology, Japan)
“Robustness and plasticity in regulatory Tcell differentiation”
Lucienne Chatenoud (Hôpital Necker-Enfants Malades, France)
To be announced
Ann Marshak-Rothstein (University of Massachusetts, USA)
“TLR-dependent detection of apoptotic debris”
Josef Smolen (Medical University of Vienna, Austria)
“Novel pathogenetic and therapeutic insights in rheumatoid arthritis”
Hartmut Wekerle (Max Planck Institute of Neurobiology, Germany)
To be announced
Pierre Miossec (University of Lyon, France)
“IL-17 family members: contribution to joint inflammation and destruction”
Sander van Deventer (Leiden University Medical Center, The Netherlands)
“Treatment of immune -mediated inflammatory disease: past and future”
Bana Jabri (University of Chicago, USA)
“Interplay between adaptive and innate immunity in celiac disease”
Garrison Fathman (Stanford University School of Medicine, USA)
“Tissue- and age-specific changes in gene expression in autoimmune diabetes”
Virginia Pascual (Baylor Institute for Immunology Research, USA)
“A genomic approach to understand human autoimmune diseases”
Frank Nestle (Guy's Hospital, UK)
“Skin inflammation: from genes to function and targeted therapy”
Edward Wakeland (UT Southwestern Medical Center at Dalls, USA)
To be announced
Eric Meffre (Yale University School of Medicine, USA)
“Human B-cell tolerance checkpoints in health and autoimmunity”
Gabriel Nunez (University of Michigan)
“Function of NLRs in innate immunity and disease”